This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing.
More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.
P2Y12 Antibody FITC Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply Rabbit monoclonal [EPR18611] to P2Y12 Suitable for: IP, WB Reacts...
BCL2L10 Polyclonal Antibody Species Reactivity Human, Mouse, Rat Host/Isotype Rabbit / IgG Class Polyclonal Type Antibody Immunogen KLH conjugated synthetic peptide derived from human BCL2L10,...